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Education

• 1984: Abitur - German High School diploma
• 1984-1991: Medical study, University of Münster, Germany
• 1991: Final exam, MD
• 1991: Approbation - (German medical license)
• 1991: Thesis (M.D., German Doctor medicinae, Dr. med.): "The influence of LH and/or FSH on spermatogenesis and morphology of Leydig- and Sertoli cells after hypophysectomy of the Djungarian hamster, Phodopus sungorus pallas" at the Medical Faculty of the University, Münster (Magna cum laude)
• 1991-1994 (Institute of Reproductive Medicine, University Münster): 3 ½ years of training in andrology and reproductive medicine at the Institute of Reproductive Medicine of the University, Münster, WHO Collaborating Center for Research in Human Reproduction, Director Univ.-Prof. Dr. med. E. Nieschlag.
• January 1, 1995-Present (Department of Urology, University Münster): Training in urology at the Department of Urology of the University, Münster, Director: Univ.-Prof. Dr. med. L. Hertle

Professional qualifications:

• 1997: Certified Clinical Andrologist of the European Academy of Andrology
• 2001: Certified Urologist (German Medical Board)
• 2001 - present: Senior registrar (Oberärztin) at the Department of Urology of the University, Münster
• 2001: Habilitation / Venia legendi for Urology

Scientific main topics:

• 1991-1992: in situ-hybridisation of testicular tissue for the detection of FSH-receptor mRNA (in collaboration with Dr. Gromoll, Institute of Reproductive Medicine) 
• 1992-1997: Clinical studies for the development and use of GnRH-antagonists and/or different testosterone preparations for male contraception (Phase I and II-studies) (in collaboration with Prof. Nieschlag and Prof Dr. Behre, Institute of Reproductive Medicine)
• Clinical studies for the use of different testosterone preparations for the treatment of male hypogonadism (in collaboration with Prof. Nieschlag and Prof. Dr. Behre, Institute of Reproductive Medicine).
• 1992-1995: Evaluation of the efficacy of gonadotropin and GnRH-treatment in patients with hypogonadotropic hypogonadism.
• Clinical study for the use of recombinant human FSH for the treatment of patients with hypopituitarism (Phase III-study).
• Cryopreservation of semen in adolescent and adult patients with oncological diseases.
• Evaluation of the diagnostic value of scrotal sonography in relation to testicular histology
• Immunohistochemical characterisation of spermatogenesis in infertile men and patients with testicular tumor or carcinoma in situ (collaboration with Prof. Dr. Bergmann, Department of Veterinary Anatomy and Embryology, Justus-Liebig-University, Gießen, Germany).
• Evaluation of testicular histology in respect to the outcome of microsurgical epididymal sperm aspiration and testicular sperm extraction (collaboration with PD Dr. Behre, Institute of Reproductive Medicine and Professor Dr. Bergmann, Department of Anatomy and Cell Biology of the University, Halle, Germany).
• Evaluation of surgical sperm retrival techniques (MESA or TESE) in combination with the intracytoplasmic sperm extraction (cooperation with the Institute of Reproductive Medicine and Department of Gynecology and Obstetrics of the University, Münster)
• Diagnostic safety of testicular biopsy in detecting carcinoma in situ.
• Sexuality, fertility and quality of life in patients with testicular tumors after oncological treatment.

Investigator/co-investigator/participation in prospective multicentre clinical trials (since 1995):

• Treatment of patients with erectile dysfunction by intracavernous injection therapy with moxisylyte (10 or 20 mg).
• Treatment of patients with Peyronie´s disease with Potaba-GlenwoodÒ versus Placebo (multicenter double-blind study of the Arbeitskreis Andrology of the German Society of Urology)
• Treatment of clinical stage I seminomas (carboplatin versus radiotherapy), Study of the Arbeitsgemeinschaft Urologische Onkologie (Section Urological Oncology) of the German Cancer Society (AH04/95)
• Treatment of clinical stage II seminomas (carboplatin), Study of the Arbeitsgemeinschaft Urologische Onkologie (Section Urological Oncology) of the German Cancer Society (AH02/94)
• Treatment of clinical stage I non-seminomatous germ cell tumors (retroperitoneal lymph node dissection versus risk-adopted treatment with chemotherapy or surveillance), Study of the Arbeitsgemeinschaft Urologische Onkologie (Section Urological Oncology)f (AH01/94)
• Randomized Phase II/III-Study of Taxol-BEP versus BEP in patients with Intermediate Prognosis Germ Cell Cancer (EORTC Protocoll 30983)
• Investigation of Positrone-Emission-Tomography (PET) in the therapeutic managment of patients with germ cell cancer (multi center study) (DKG/AUO)

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